CKD / Mineral bone disease

Ckd-mineral and Bone Disorders (ckd-mbd)

[Chronic kidney disease-mineral and bone disorder (CKD-MBD)].

Changes in mineral and bone metabolism are prevalent in chronic kidney disease. There are several types of renal bone disease, called 'renal osteodystrophy (ROD)'. ROD includes osteitis fibrosa, osteomalacia, adynamic bone disorder, and mixed osteodystrophy. Osteitis fibrosa is high turnover bone due to secondary hyperparathyroidism. Osteomalacia is low turnover bone concomitant of increased os...

The New Kidney and Bone Disease: Chronic Kidney Disease – Mineral and Bone Disorder (CKD–MBD)

Kidney is one of the most important organs in the regulation of mineral metabolism (Fukagawa et al., 2006). Chronic kidney disease (CKD) is a worldwide public health problem that affects 5% to 10% of the world population, with increasing prevalence and adverse outcomes, including progressive loss of kidney function, cardiovascular disease, and premature death (Eknoyan et al., 2004). Calcium and...

[Brazilian Guidelines for bone and mineral disorders in CKD children].

1.1 Os níveis séricos de cálcio (Ca), fósforo (P), fosfatase alcalina (FA), paratormônio-intacto (PTH), pH e bicarbonato sérico (HCO3) ou reserva alcalina (CO2 total) devem ser determinados em todas as crianças e adolescentes nos estágios II a V da doença renal crônica (DRC). A frequência dessas determinações deve ser baseada na presença e na magnitude das alterações e na velocidade de progress...

Bisphophonates in CKD Patients with Low Bone Mineral Density

Patients with chronic kidney disease-mineral and bone disorder (CKD-MBD) have a high risk of bone fracture because of low bone mineral density and poor bone quality. Osteoporosis also features low bone mass, disarranged microarchitecture, and skeletal fragility, and differentiating between osteoporosis and CKD-MBD in low bone mineral density is a challenge and usually achieved by bone biopsy. B...